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Isabel Rozas Selected Research

Guanidine (Guanidine Nitrate)

3/2022Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity.
2/2022A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
12/2020Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives.
4/2018Effect of isouronium/guanidinium substitution on the efficacy of a series of novel anti-cancer agents.
1/2006Computational study of antagonist/alpha1A adrenoceptor complexes--observations of conformational variations on the formation of ligand/receptor complexes.

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Isabel Rozas Research Topics

Disease

7Neoplasms (Cancer)
03/2022 - 11/2009
2Breast Neoplasms (Breast Cancer)
04/2018 - 01/2013
1Multiple Myeloma
02/2022
1Uterine Cervical Neoplasms (Cancer of the Cervix)
04/2018
1Colorectal Neoplasms (Colorectal Cancer)
10/2015
1Depressive Disorder (Melancholia)
02/2013
1Neuroblastoma
01/2013
1Edema (Dropsy)
01/2013
1Schizophrenia (Dementia Praecox)
06/2009
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2006

Drug/Important Bio-Agent (IBA)

5Guanidine (Guanidine Nitrate)FDA Link
03/2022 - 01/2006
2DNA (Deoxyribonucleic Acid)IBA
03/2022 - 11/2009
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
02/2022
1phenylguanidineIBA
12/2020
1Schiff Bases (Schiff Base)IBA
11/2019
1Antineoplastic Agents (Antineoplastics)IBA
11/2019
1diphenyl (biphenyl)IBA
11/2019
1TinIBA
11/2019
1AmidesIBA
04/2018
1CationsIBA
04/2018
1Phosphotransferases (Kinase)IBA
06/2014
1Sorafenib (BAY 43-9006)FDA Link
06/2014
1Norepinephrine (Noradrenaline)FDA LinkGeneric
02/2013
1resazurinIBA
01/2013
1CarrageenanIBA
01/2013
1Antidepressive Agents (Antidepressants)IBA
06/2009
1Adrenergic Receptors (Adrenergic Receptor)IBA
01/2006
1QuinazolinesIBA
01/2006

Therapy/Procedure

2Therapeutics
10/2015 - 06/2009